Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
USERS' SCORE
Good
Based on 88 Reviews
8.1
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Melatonin
10 mg
*
Top Medical Research Studies
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Most Useful Reviews
10
Effective sleep aid
6 people found this helpful
This product helps me sleep effectively.
9
Effective melatonin use
3 people found this helpful
I was taking 10 mg Amitriptyline but realised I needed to change my sleep-inducing medication due to its side effects. After being recommended Melatonin, I decided to try it after stopping Amitriptyline for 7 days. I am extremely satisfied with the results and would suggest using it on an experimental basis, as individual responses vary. If anyone requires more details, feel free to ask.
9
Delicious sleep supplement
3 people found this helpful
Keep this at your bedside and take 1-2 tablets about 30 minutes before sleep. It looks like candy, making it tempting to take. It worked wonderfully for me; I don’t wake up throughout the night and can sleep soundly until morning, feeling refreshed upon waking. It’s highly recommended for those suffering from insomnia.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
- All Researches
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
7
We explored REM sleep behavior disorder (RBD) as a complex condition that can be linked to a variety of underlying disorders. Through a literature review and insights from foundational texts, we recognized that RBD may emerge at any age and can initially appear as an isolated issue or be associated with other significant conditions like Parkinson’s and narcolepsy.
Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
User Reviews
USERS' SCORE
Good
Based on 88 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
10
Effective sleep aid
6 people found this helpful
This product helps me sleep effectively.
9
Effective melatonin use
3 people found this helpful
I was taking 10 mg Amitriptyline but realised I needed to change my sleep-inducing medication due to its side effects. After being recommended Melatonin, I decided to try it after stopping Amitriptyline for 7 days. I am extremely satisfied with the results and would suggest using it on an experimental basis, as individual responses vary. If anyone requires more details, feel free to ask.
9
Delicious sleep supplement
3 people found this helpful
Keep this at your bedside and take 1-2 tablets about 30 minutes before sleep. It looks like candy, making it tempting to take. It worked wonderfully for me; I don’t wake up throughout the night and can sleep soundly until morning, feeling refreshed upon waking. It’s highly recommended for those suffering from insomnia.
9
Restful sleep
2 people found this helpful
Natrol Melatonin Fast Dissolve Maximum Strength 10 mg tablets have revolutionised my sleep routine. The fast-dissolving feature aids quick absorption for a restful night, while the maximum strength promotes relaxation. The citrus flavour is enjoyable and makes it easy to take. It's a fantastic value, and I highly recommend it!
9
Great for jet lag
2 people found this helpful
Excellent product! I’m about to repurchase. It’s the best melatonin I’ve used. The extra strength and dissolvable tablets allow me to take one half an hour before sleep. The resulting drowsiness is delightful. This product offers a great night’s sleep, excellent for jet lag or the disruption caused by daylight savings. Good price and service from iHerb.
Frequently Asked Questions
9
Sound sleep achieved
2 people found this helpful
Fantastic! From the first night I tried this, it worked wonders. I've struggled with lack of sleep for ages, but this product had me asleep within 20 minutes for a solid 9 hours without waking once. Highly recommend it. The taste is a bit unusual but becomes pleasant over time.
9
Quick sleep aid
1 people found this helpful
I find these 10mg melatonin tablets amazing; I take one tablet and I'm off to sleep within 30 minutes. I highly recommend them.
9
Regulated circadian rhythms
1 people found this helpful
This medication is excellent for regulating circadian rhythms and addressing recurrent insomnia. My neurologist recommended it, and since starting about three months ago, my sleep has improved significantly. I highly recommend it for anyone experiencing similar issues.
9
Effective melatonin use
3 people found this helpful
I was taking 10 mg Amitriptyline but realised I needed to change my sleep-inducing medication due to its side effects. After being recommended Melatonin, I decided to try it after stopping Amitriptyline for 7 days. I am extremely satisfied with the results and would suggest using it on an experimental basis, as individual responses vary. If anyone requires more details, feel free to ask.
9
Overcame dependency
1 people found this helpful
I managed to wean myself off sleeping pills! As a woman in my 50s with long-standing difficulty falling asleep, I've relied on sleeping aids for years. Thanks to melatonin, I've freed myself from dependence! I divide a 10mg tablet into smaller doses and take it about an hour before I want to sleep, and I can now fall asleep smoothly.
10
Life-changing sleep
1 people found this helpful
Fantastic product! For nearly 30 years, I could never sleep for more than 3 hours in a 24-hour period. This product has given me a new lease on life, allowing me to now sleep a minimum of 8 hours! I recommend this to anyone struggling with sleep. Even when needing only 5 hours, I don't feel fatigued.
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
References
- Wei Z, Shen H, Wang F, Huang W, Li X, et al. Melatonin mediates intestinal barrier dysfunction and systemic inflammation in moderate-severe OSA patients. Ann Med. 2024;56:2361825. doi:10.1080/07853890.2024.2361825
- Motlaq TM, Rahimi B, Amini S. Effect of melatonin on insomnia and daytime sleepiness, in patients with obstructive sleep apnea and insomnia (COMISA): A randomized double-blinded placebo-controlled trial. J Pharm Health Care Sci. 2024;10:25. doi:10.1186/s40780-024-00347-9
- Dastan F, Gholizadeh Niari B, Adimi Naghan P, Barati S, Eskandari R. Evaluating the Effects of Agomelatine on Polysomnography Parameters in Patients with Obstructive Sleep Apnea. J Pharm Pharm Sci. 2023;25:418. doi:10.18433/jpps33252
- Schenck CH. REM sleep behavior disorder as a complex condition with heterogeneous underlying disorders: clinical management and prognostic implications [Commentary]. Sleep Breath. 2022;26:1289. doi:10.1007/s11325-022-02574-6
